Experience:
Assistant Professor and Underwood Prescott Career Development Chair, Massachusetts Institute of Technology
Co-founder, BioBits®
Postdoctoral Fellow, Stanford University
PhD, Northwestern University
Dr. Stark’s career is marked by her pioneering work in developing biological technologies to unlock the vast potential of cell-surface sugars, known as glycans, for immunological discovery and immunotherapy. Glycans form a protective layer on the surface of every cell, influencing immunological processes. Despite their significance, drug developers’ ability to identify the specific glycans that regulate immune responses and design targeted therapies remains limited. Dr. Stark’s lab is at the forefront of efforts to comprehend and manipulate the roles of glycans in the immune system, aiming to 1) bridge crucial gaps in immunobiology and 2) forge the path for next-generation immunotherapies.
As a postdoctoral fellow with Nobel Laureate, Professor Carolyn Bertozzi at Stanford University, Jessica’s work focused on identifying and targeting glycans. She is a co-inventor of antibody-lectin chimeras (AbLecs), a modular platform for glyco-immune checkpoint blockade. She received her PhD in chemical and biological engineering with Professor Michael Jewett at Northwestern University. Dr. Stark is currently an Assistant Professor in the departments of Biological and Chemical Engineering at MIT and an intramural faculty member in MIT’s Koch Institute for Integrative Cancer Research.
